Pediatric liver mass + elevated AFP, suspected hepatoblastoma
Recommended: MRI Abdomen + AFP + CT Chest for staging is the preferred imaging study for pediatric liver mass + elevated afp, suspected hepatoblastoma. Most common pediatric primary liver malignancy, typically < 3 years.
Recommended study
MRI Abdomen + AFP + CT Chest for staging
Most common pediatric primary liver malignancy, typically < 3 years. AFP markedly elevated.
If the default doesn't apply
Pulmonary metastatic disease assessment
CT
CT Chest
IV contrast
Watch-outs
Beckwith-Wiedemann / FAP / Trisomy 18 association
Screen at-risk children; abdominal US + AFP per protocol.
Pearls
- PRETEXT staging (I-IV) based on liver sectors involved.
- Chemotherapy + surgical resection; liver transplant for unresectable.
- Survival > 80% in early-stage disease.