Chest pain, adult — undifferentiated, imaging triage
Recommended: CXR (PA + lateral), then targeted CT by phenotype is the preferred imaging study for chest pain, adult — undifferentiated, imaging triage. Start with CXR — fast, broad differential (pneumothorax, effusion, consolidation, widened mediastinum, rib fracture).
CXR (PA + lateral), then targeted CT by phenotype
Start with CXR — fast, broad differential (pneumothorax, effusion, consolidation, widened mediastinum, rib fracture). Targeted CT follows the clinical phenotype: pleuritic + tachypnea / Wells-positive → CTPA; tearing or interscapular pain + HTN / widened mediastinum → ECG-gated CTA chest dissection protocol; exertional ischemic pattern → CCTA or stress imaging. Bedside lung US complements CXR (absent lung sliding, B-lines, consolidation).
If the default doesn't apply
Watch-outs
Small pneumothorax, focal consolidation, or rib fracture often answers the question without advanced imaging.
Keep aortic dissection AND ACS on the differential — consider CTA chest and cardiac imaging.
Positive predictive value is modest; CTA confirms before quoting a diagnosis.
Pearls
- Bedside lung US beats supine CXR for pneumothorax (absent lung sliding) and effusion.
- Wells / PERC drive whether CTPA is the right next test — D-dimer guides the gate.
- Negative CTPA + negative CTA chest doesn't rule out ACS — different test for different anatomy.