Acute dyspnea or pleuritic chest pain
Recommended: CT Pulmonary Angiogram (CTPA) is the preferred imaging study for acute dyspnea or pleuritic chest pain. Risk-stratify with Wells / PERC and d-dimer before imaging.
Recommended study
CT Pulmonary Angiogram (CTPA)
Risk-stratify with Wells / PERC and d-dimer before imaging. CTPA is the modality of choice when imaging is indicated.
If the default doesn't apply
Pregnancy
US
Bilateral LE Doppler → V/Q if negative
No contrast
Iodinated contrast contraindicated
NM
V/Q scan
No contrast
Already on therapeutic anticoag, low concern
Often no imaging needed
No contrast
Watch-outs
PERC negative / Wells low
Do not image — d-dimer first or no work-up.
Hemodynamically unstable
Consider bedside echo over delayed CTPA; activate massive PE pathway.
Pearls
- Subsegmental PE on CTPA — incidence rising with detector resolution; clinical context dictates treatment.
- 20G antecubital IV or larger required for CTPA bolus timing.